Alexis Adian Smith (Lexi)

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Los Angeles + 1.213.243.2653

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Lexi Smith is a trial lawyer who handles high-stakes intellectual property disputes for innovators in pharmaceuticals, biotechnology, consumer electronics, agriculture, and other technology-driven industries. Her practice covers the full range of IP and business litigation: patent infringement, trade secret misappropriation, licensing disputes, trademark and copyright infringement, unfair competition, breach of contract, and related business torts. The Los Angeles Business Journal named Lexi to its list of "Top 100 Lawyers of Los Angeles 2026."

Lexi has a strong record at trial and in other evidentiary proceedings. In patent litigation over a method of treating non-small cell lung cancer, she examined several witnesses at a five-day jury trial. The jury deliberated for less than three hours before awarding Jones Day's client more than $100 million. More recently, after a week-long evidentiary hearing, she helped Jones Day's client vacate an ongoing royalty award.

Lexi's work spans every major forum for IP disputes. In arbitration, she obtained a unanimous award for a biotechnology company on claims for breach of a gene therapy license. She has litigated multiple matters involving vaporizing technology in federal district courts, in investigations before the U.S. International Trade Commission, and on appeal at the U.S. Court of Appeals for the Federal Circuit.

Lexi is equally skilled at winning decisive results before trial, having recently won summary judgment of both noninfringement and invalidity for a client.

Before becoming a lawyer, Lexi spent four years as a practicing chemical engineer.

Expérience

  • E. & J. Gallo Winery knocks out Vineyard Investigations' patent infringement case on summary judgmentJones Day successfully defended E. & J. Gallo Winery ("Gallo") in a three-patent dispute brought by Vineyard Investigations in the Eastern District of California.
  • Sila asserts patent infringement at ITC involving battery innovationsJones Day represents Sila Nanotechnologies, Inc. ("Sila") and Georgia Tech Research Corporation in a Section 337 investigation before the U.S. International Trade Commission (ITC) and the Eastern District of Texas.
  • R.J. Reynolds asserts patent in ITC trial against dozens of respondents over disposable vaporizersOn behalf of R.J. Reynolds ("Reynolds") entities, Jones Day successfully obtained a Final Initial Determination and Recommended Determination on Remedy and Bond in Reynolds's favor in a Section 337 patent infringement investigation before the International Trade Commission (ITC).
  • Pharmaceutical company wins $107.5 million jury verdict in patent dispute involving AstraZeneca's lung cancer treatment Tagrisso®Jones Day on behalf of a pharmaceutical company won a jury award of $107.5 million in damages after a five-day trial and less than three hours of jury deliberation.
  • R.J. Reynolds successfully enforces patents in ITC trial against Philip Morris in dispute over cigarette alternativeJones Day's client Reynolds achieved a precedent-setting victory before the International Trade Commission (ITC) against its main competitors Philip Morris Products S.A. ("Philip Morris") and Altria Client Services LLC ("Altria") in a patent infringement dispute involving tobacco heating and vaping products.
  • Merck unit resolves DJ action involving pneumococcal vaccine patentsJones Day represented Merck Sharp & Dohme Corp. in an action in Delaware district court against Pfizer (through its subsidiaries including Wyeth, LLC) involving several patents on Wyeth’s vaccine technology.
  • REGENXBIO wins unanimous award of over $33 million issued against former licensee in AAA arbitrationJones Day, on behalf of REGENXBIO Inc., secured a unanimous final award of over $33 million from a three-member AAA panel following a multi-day arbitration against REGENXBIO's licensee Abeona Therapeutics Inc.
  • GTAT protects trade secrets, obtains restraining order against former employeeJones Day assisted GT Advanced Technologies (GTAT), a leader in providing technology solutions to the solar industry, in pursuing claims of trade secret misappropriation and breach of contracts against a former employee when he departed the company after over a decade of exposure to its trade secrets and confidential information.
  • Lam Research attempts merger with KLA-TencorJones Day represented Lam Research Corporation in its proposed acquisition of all outstanding shares of KLA-Tencor Corporation in a cash and stock transaction that placed an equity value on KLA-Tencor of approximately $10.6 billion based on its closing stock price on October 20, 2015.
  • Riverside acquires Sina Pearson TextilesJones Day advised The Riverside Company in connection with its acquisition of Sina Pearson Textiles Inc., a contract textile supplier that designs and distributes fabric to architectural and design firms.
  • Riverside acquires Momentum GroupJones Day advised The Riverside Company in connection with the acquisition and related financing of the Momentum Group, an award-winning and industry-leading distributor of commercial interior fabrics, wallcoverings, and related products.
  • DIRECTV and component manufacturers prevail on summary judgment in patent infringement caseJones Day representing The DIRECTV Group, Inc., as well as numerous manufacturers of components used in DIRECTV's systems, prevailed by obtaining summary judgment rulings holding: (1) that a covenant not to sue between DIRECTV and Global was breached by Global's filing of this lawsuit; and (2) that the component manufacturers did not infringe Global's patents.
  • Celgene invests in and enters into strategic collaboration with NantBioScienceJones Day represented Celgene Corporation, a biopharmaceutical company, in connection with its purchase of $75 million of Series A Preferred Stock in a private placement by NantBioScience, a subsidiary of NantWorks, LLC and a biopharmaceutical company focused on the discovery of innovative treatments by developing molecularly targeted drugs.
  • Lesso America defends use of LESSO trademarkChina Lesso Group Holdings Limited/Lesso America retained Jones Day to defend it against claims of trademark infringement brought by Lasco Fittings in the United States District Court for the Central District of California.
  • DIRECTV defeats patent infringement charges over broadcast satellite TVJones Day defended DIRECTV and related companies in a patent infringement action involving multiple patents allegedly reading on aspects of its television satellite broadcast technology.
  • Mag Instrument prevails in opposition against MAGSTUD markJones Day brought a trademark opposition on behalf of Mag Instrument, Inc. against MAGSTUD mark application for magnetic stud finders.
  • Mag Instrument successfully challenges use of infringing domain name in UDRP proceedingJones Day successfully represented Mag Instrument, Inc. in a domain name dispute under the UDRP before the WIPO Arbitration and Mediation Center in connection with the infringing domain name maglite.me.
  • Mag Instrument asserts trademark infringement and unfair competition action against tool companyJones Day represents Mag Instrument, Inc. in a trademark infringement and unfair competition action against a tool and equipment supply company. 
  • Tokyo Electron acquires FSI International, leading provider of cleaning and surface preparation equipment, for $252.5 millionJones Day advised Tokyo Electron Limited, a leading manufacturer of semiconductor manufacturing equipment, in connection with its acquisition of FSI International, Inc., a leading provider of cleaning and surface preparation equipment, for $252.5 million.
  • ABB acquires wireless technology company Tropos NetworksJones Day advised ABB in its acquisition of Tropos Networks Inc., a Silicon Valley-based company that develops and markets wireless technologies and products for distribution area communication networks.
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    May 13, 2026 Webinars

    Litigating Trade Secrets in the ITC

    September 2014 External Publications

    Four Lessons in Challenging Trademark Use in TTAB Proceedings, INTABulletin, Vol. 69 No. 16

    May 13, 2026 Webinars

    Litigating Trade Secrets in the ITC

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